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U.S. News · Investor Protection · M11

Regulators Say Martin Shkreli Traded More Than 60 Drug Stocks on YouTube Despite a Lifetime Ban

Martin Shkreli streams trading sessions that run past nine hours. A judge barred him from owning drug stocks in 2022. Regulators now want him held in contempt, stripped of the stocks and fined every dollar of profit.

By Sean Anees Saifi · Capital Wealth · Published Friday, October 16, 2026 · Source: The Wall Street Journal, Wednesday, October 14, 2026, whose market figures are the Tuesday, October 13 close (U.S. News)
Key Points
$750
Daraprim's price per pill after his 2015 increase, from under $20
60
drug companies whose shares regulators say he's held since 2022
$841,000
his brokerage account after a 2024 trial failure, up from $138,200
$10 million
account in the livestreamed trading challenge begun in June, per the filing
An empty black office chair sits on a polished trading floor beneath a curved wall of red and green price tickers, traders blurred behind it.
Regulators say the livestreams run past nine hours, with call-in segments where viewers ask for investing advice.
In one line: Regulators say a man banned from drug stocks for life traded them on YouTube for years, so vet the picker before the pick.

Martin Shkreli goes live several times a week. The streams run past nine hours. Viewers call in with investing questions. On Tuesday, Oct. 13, the Federal Trade Commission and seven states told a federal judge in Manhattan what they think of that. A judge barred him from owning drug stocks in 2022. Regulators say he's been trading them on camera anyway.

Here's the record, as the Journal's Xavier Martinez lays it out. Shkreli is 43. In 2015 the company he ran bought an old anti-parasite drug, Daraprim, and raised the price to $750 a pill from less than $20. He defended it loudly online and became known as the "pharma bro." In 2017 a jury convicted him of securities fraud. Prosecutors said he cheated his hedge-fund investors and used his drug company's money to pay them back. He got seven years and was released early in 2022.

That same year a federal judge barred him from owning stakes in drug companies and from making public statements meant to sway their business. The judge found his old company had illegally blocked a generic rival to Daraprim. Regulators now allege he ignored both rules. Their filing says he's held shares of more than 60 drug companies since 2022. It says he often put his brokerage screen on the stream for everyone to see.

Betting on failure

The trades ran one way, regulators say. He shorted companies such as Cassava Sciences (SAVA), INmune Bio (INMB), aTyr Pharma (ATYR) and Capricor Therapeutics (CAPR). A short is a bet that a stock falls. Three of the four had key drugs fail in trials. After Cassava's Alzheimer's drug failed in November 2024, his Interactive Brokers (IBKR) account grew from $138,200 to $841,000, the filing alleges. In June he began a new on-air trading challenge with a $10 million account, regulators say. They say he's now short Sellas Life Sciences (SLS) and has told viewers its leukemia study will fail.

Regulators want him to sell the stocks and pay a fine equal to every dollar of trading profit since February 2022, with no credit for losses. They're asking for rising fines and jail if he refuses. He didn't respond to the Journal. New York's attorney general said in a release that his actions "put investors and the public at risk." These are allegations. A judge hasn't ruled.

Our read

This is Insurance/Consumer Protection (M11). The planning lesson is about the stream, and it holds for any stream. A stock tip arrives with a face and a confident voice. It rarely arrives with a record. Here the record is public. A fraud conviction. A lifetime ban. And, regulators say, a run of bets that a drug trial fails. Biotech trades like that are binary. One press release and the stock can lose most of its value, or double, before you've read the headline. Nobody on a call-in show owes you a thing when it goes the wrong way.

The piece of your plan this touches is your own brokerage app, and the list of people you let into it. The check this week has two steps. First, open the app and look at your five smallest positions. For each one, name where the idea came from. If the answer is a stream, a post or a call-in show, you own a tip, and a tip isn't a plan. Second, take the name of anyone whose picks you follow and run it through FINRA's BrokerCheck and a plain news search. It takes five minutes. Shkreli's history was one search away the whole time. If a position fails the first step, bring it to a review before you add to it. You don't test the smoke alarm by waiting for smoke.

What It Means For Your Portfolio

Avoid. Never trade a biotech on a livestreamer's call

No portfolio action. A stock picker's record matters more than the pick, and this one includes a fraud conviction and a lifetime ban.

General planning principles, not advice for anyone in particular. Before you act on anyone's stock call, look up the person. FINRA's BrokerCheck and the SEC's enforcement lookup are public. A past fraud conviction or an industry ban ends the conversation.

Treat a drug stock ahead of a trial result as a bet, and size it that way. If you make it at all, keep it small enough that a total loss changes nothing about your month.

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